Data Collection in EuroSIDA
A data collection form is completed by the sites at the time of enrolment and annually hereafter on to a standardized data collection form. From follow-up Winter 2014/2015 (DS41), all data collection is in the electronic CRF system, REDCap at https://chip-crf.info/redcap/. Access of a test version of this form is available upon request.
For each patient, the date of HIV diagnosis and way of transmission is recorded. The date of diagnosis of all AIDS defining diseases are recorded, using the 1993 Centers for Disease Control and Prevention definitions. Further, the date of starting and stopping each antiretroviral drug is recorded, as is the use of drugs for prophylaxis against opportunistic infections. All CD4 lymphocyte counts and viral load measurements are requested at every follow-up, as well as a range of other laboratory values. Further, data about non-AIDS defining diseases, adverse events of anti-HIV drugs (D:A:D-events), and causes of death (CoDe) are collected. In addition, a plasma sample is requested from all patients every 6 months. This plasma sample is stored locally at minus 80 degrees centigrade, and intermittently shipped to the central repository at the coordinating centre in Copenhagen.
Staff from the coordinating office visit all centres regularly to ensure correct patient selection and that accurate data was provided. All sites complete the follow-up forms within a two month period, after which the forms are sent to the coordinating centre for data entry. An updated version of the database is usually available 3 months later, allowing the study to provide almost real-time data on the patients followed.
For more information about the EuroSIDA study, please contact the Coordinating Centre at: email@example.com
EuroSIDA study documents
Instructions for EuroSIDA data collection FU45 (Autumn 2017)
SOP for electronic data collection ds45 (Autumn 2017)
EuroSIDA-RESPOND Electronic Submision Tool - Guide (Autumn 2017)
List of Definitions on Clinical Events (Autumn 2017)
Case definitions INSTI Hypersensitivity Reaction/Liver Toxicity
RESPOND Manual of Operations (MOOP)
Criteria for participation in the EuroSIDA study
REDCap instructions (Video) (2014)
Information on plasma collection
Sample INSTI HSR form
The most recent HICDEP protocol may be found here
Access to a test version of the REDCap form is available upon request. Please send an email to: firstname.lastname@example.org