The Royal Free HIV Cohort Study (RFHCS)
has been running since the early 1990s. It is a single centre, observational study of people attending for HIV care at the Royal Free Hospital, London, UK. Publications and ongoing projects based on using the database address questions concerning HIV prognosis and management; in particular gender and socio-economic issues, development of toxicities, and trends over time in morbidity, mortality and treatment response. The clinical lead for the study is Professor Margaret Johnson, and the statistical leads are Dr Fiona Lampe and Dr Colette Smith.